Ricarda MARKO

Bachelor's thesis

Counteracting constitutive activity of Orai1 with an H171Y mutation

Counteracting constitutive activity of Orai1 with an H171Y mutation
Abstract:
The functions and structures of the Orai1-ANSGA mutation are still not completely known. To further investigate possible changes in pore structure, Orai1 ANSGA and H171Y in combination with different amino acids were used in cysteine-crosslinking studies, to see if the ANSGA and H171Y mutations affect the orientation of pore-lining residues.
 

Keywords

Ion channels Ca2+ channels Orai1 ANSGA cysteine-crosslinking H171Y
 
Language used: Czech
Date on which the thesis was submitted / produced: 22. 10. 2021

Thesis defence

  • Supervisor: Mgr. Irene Frischauf, Ph.D.

Citation record

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MARKO, Ricarda. Counteracting constitutive activity of Orai1 with an H171Y mutation. České Budějovice, 2021. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

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  • Soubory jsou od 22. 10. 2024 dostupné: světu
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UNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE

Faculty of Science

Bachelor programme / field:
Biochemistry / Biological Chemistry

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