NOVEL ROLE OF HEATR1 IN RIBOSOME BIOGENESIS AND DNA DAMAGE SIGNALING – Zsófia TURI, M.Sc.
Zsófia TURI, M.Sc.
Doctoral thesis
NOVEL ROLE OF HEATR1 IN RIBOSOME BIOGENESIS AND DNA DAMAGE SIGNALING
NOVEL ROLE OF HEATR1 IN RIBOSOME BIOGENESIS AND DNA DAMAGE SIGNALING
Abstract:
In this work, we identified a nucleolar protein, HEATR1 as an important player of ribosome biogenesis. In the absence of this protein, ribosome biogenesis stress is activated, characterized by the elevated level of p53, cell cycle arrest and structural changes of the nucleolus. Furthermore, HEATR1 seems to be involved in the early steps of ribosome biogenesis, since it possesses similar localization …moreAbstract:
In this work, we identified a nucleolar protein, HEATR1 as an important player of ribosome biogenesis. In the absence of this protein, ribosome biogenesis stress is activated, characterized by the elevated level of p53, cell cycle arrest and structural changes of the nucleolus. Furthermore, HEATR1 seems to be involved in the early steps of ribosome biogenesis, since it possesses similar localization …more
Language used: Czech
Date on which the thesis was submitted / produced: 30. 4. 2019
Thesis defence
- Date of defence: 26. 11. 2019
- Supervisor: Ing. Pavel Moudrý, Ph.D.
Citation record
ISO 690-compliant citation record:
TURI, Zsófia. \textit{NOVEL ROLE OF HEATR1 IN RIBOSOME BIOGENESIS AND DNA DAMAGE SIGNALING}. Online. Doctoral theses, Dissertations. Olomouc: Palacký University Olomouc, Faculty of Medicine and Dentistry. 2019. Available from: https://theses.cz/id/1n0h9z/.
The right form of listing the thesis as a source quoted
TURI, Zsófia. NOVEL ROLE OF HEATR1 IN RIBOSOME BIOGENESIS AND DNA DAMAGE SIGNALING. Olomouc, 2019. disertační práce (Ph.D.). UNIVERZITA PALACKÉHO V OLOMOUCI. Lékařská fakulta
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Institution archiving the thesis and making it accessible: UNIVERZITA PALACKÉHO V OLOMOUCI, Lékařská fakultaPalacký University Olomouc
Faculty of Medicine and DentistryDoctoral programme / field:
Pediatrics / Pediatrics
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