Bc. Alexandra Skysľaková

Bachelor's thesis

Software for the detection of strand bias from the next-generation sequencing data

Software for the detection of strand bias from the next-generation sequencing data
Abstract:
V posledných rokoch prinieslo sekvenovanie novej generácie (NGS) významný pokrok v oblasti genomického výskumu a diagnostiky. NGS ponúka možnosť rýchleho, ľahko dostupného a lacného sekvenovania DNA, no stále prináša i pomerne veľa chýb. Jedným z nich je strand bias, ktorý je tiež hlavnou témou tejto práce. Strand bias je typ biasu vznikajúci, keď je informácia získaná z jedného reťazca DNA nadmerne …more
Abstract:
In recent years, next-generation sequencing (NGS) has brought significant progress to genomic research and diagnostics by making sequencing of the DNA fast, available and cheap. However, NGS is still prone to many errors. One of them is strand bias, which is also the main topic of this thesis. Strand bias is a situation when information gained from one strand of the DNA is overrepresented in the sequencing …more
 
 
Language used: English
Date on which the thesis was submitted / produced: 19. 5. 2022

Thesis defence

  • Date of defence: 1. 7. 2022
  • Supervisor: Mgr. Monika Čechová, Ph.D.
  • Reader: Mgr. Vojtěch Bystrý, Ph.D.

Citation record

Full text of thesis

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Fakulta informatiky

Masaryk University

Faculty of Informatics

Bachelor programme / field:
Informatics / Informatics

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