Insights into the Evolutionary Conserved Mitochondrial Contact Site and Cristae Organization System in Trypaonsoma brucei Through RNA Interference – Lawrence Rudy CADENA
Lawrence Rudy CADENA
Bachelor's thesis
Insights into the Evolutionary Conserved Mitochondrial Contact Site and Cristae Organization System in Trypaonsoma brucei Through RNA Interference
Investigation of the cristae formation complex MICOS in bloodstream form Trypanosoma brucei.
Abstract:
This work aims to give insight into the evolution of the mitochondria by investigating novel properties of the evolutionary conserved mitochondrial contact site and cristae organization system complex within the Excavata clade using Trypanosoma brucei as our model. This study shows that this complex indeed contains diverse properties that are not present in the typically studied Opisthokonta clade …moreAbstract:
This work aims to give insight into the evolution of the mitochondria by investigating novel properties of the evolutionary conserved mitochondrial contact site and cristae organization system complex within the Excavata clade using Trypanosoma brucei as our model. This study shows that this complex indeed contains diverse properties that are not present in the typically studied Opisthokonta clade …more
Language used: English
Date on which the thesis was submitted / produced: 14. 5. 2018
Thesis defence
- Supervisor: doc. Mgr. Hassan Hashimi, Ph.D.
Citation record
ISO 690-compliant citation record:
CADENA, Lawrence Rudy. \textit{Insights into the Evolutionary Conserved Mitochondrial Contact Site and Cristae Organization System in Trypaonsoma brucei Through RNA Interference}. Online. Bachelor's thesis. České Budějovice: University of South Bohemia in České Budějovice, Faculty of Science. 2018. Available from: https://theses.cz/id/2j8i1l/.
The right form of listing the thesis as a source quoted
CADENA, Lawrence Rudy. Insights into the Evolutionary Conserved Mitochondrial Contact Site and Cristae Organization System in Trypaonsoma brucei Through RNA Interference. Č. Budějovice, 2018. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
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Institution archiving the thesis and making it accessible: JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH, Přírodovědecká fakultaUNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE
Faculty of ScienceBachelor programme / field:
Biochemistry / Biological Chemistry
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Investigation of MICOS in two life cycle stages of \kur{Trypanosoma brucei}
Teresa WAGNER -
The Diverged Trypanosome MICOS Complex as a Hub for Mitochondrial Cristae Shaping and Protein Import
Jiří HELLER -
Genome-wide Screen \kur{Trypanosoma brucei} for novel mitochondrial proteins
Iosif KAUROV -
Determining the role of FoF1-ATP synthase dimers in Trypanosoma brucei mitochondrial biogenesis
David HOLLAUS
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