Changes of IgM expression levels in the head kidney of \kur {Cyprinus carpio} following an infection with \kur {Sphareospora molnari}

Viktor SIERANSKI

Bakalářská práce

Changes of IgM expression levels in the head kidney of Cyprinus carpio following an infection with Sphareospora molnari

Abstract:

Sphaerospora molnar is a myxozoan inducing sphaerosporosis in common carp and causing serious damage to secondary lamellae and epithelia of the gills. The understanding of the host immune response against S. molnari as well as other myxozoans is very limited in part due to the unresolved life cycle. The focus of this thesis was the quantification of membrane bound and secretory IgM expression levels in the head kidney over a period of 9 weeks following an intraperitoneal injection of S. molnari blood stages. Significant increases in the expression levels of both IgMs were observed reaching its maximum at 42 days after infection. Two weeks following the infection the first significant increases of secretory IgM were detected.

Jazyk práce: angličtina

Datum vytvoření / odevzdání či podání práce: 11. 12. 2019

Obhajoba závěrečné práce

• Vedoucí: Astrid S. Holzer, M.Sc., Ph.D.

JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH

Přírodovědecká fakulta

Bakalářský studijní program / obor:
Biochemistry / Biological Chemistry