MUDr. Ivo Křikava, Ph.D.

Doctoral thesis

Možnosti ovlivnění kardiotoxicity bupivakainu kombinací lokálních anestetik

The effect of mixtures of local anaesthetics on bupivacaine-induced toxicity
Abstract:
Úvod: Bupivakain je široce používané lokální anestetikum. V klinické praxi je často využívána směs bupivakainu s lidokainem nebo s trimekainem s cílem dosáhnout rychlého nástupu blokády pomocí lidokainu nebo trimekainu a dlouhého trvání blokády pomocí bupivakainu. Cílem této práce bylo srovnat kardiotoxicitu vyšších dávek samotného bupivakainu a směsi bupivakainu a lidokainu (resp. trimekainu) na izolovaném …more
Abstract:
Background: Bupivacaine is a widely used long-acting local anaesthetic. In clinical practice, mixtures of bupivacaine and lidocaine or bupivacine and trimecaine are often used in order to combine the fast onset of sensory blockade by lidocaine or trimecaine with more profound and longer blockade duration caused by bupivacaine. Aim of this study was to compare the cardiotoxicity of large doses of bupivacaine …more
 
 
Language used: Czech
Date on which the thesis was submitted / produced: 4. 11. 2013

Thesis defence

  • Date of defence: 27. 11. 2013
  • Supervisor: prof. MUDr. Marie Nováková, Ph.D., prof. MUDr. Pavel Ševčík, CSc.

Citation record

Full text of thesis

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Lékařská fakulta

Masaryk University

Faculty of Medicine

Doctoral programme / field:
Anesthesiology, Intensive Medicine and Pain Management (4-years) / Anesthesiology, Intensive Medicine and Pain Management

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