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Mgr. Aneta Baumeisterová

Bachelor's thesis

Komparativní genomika hlavního histokompatibilitního komplexu

Comparative genomics of the major histocompatibility complex
Abstract:
The major histocompatibility complex (Mhc) is a complex genetic region, containing many genes with various functions. Although Mhc was first identified as an important transplantation factor, later its role in presentation of antigenic peptides to the immune system was revealed. Only class I and II genes of the Mhc encode molecules with this function. Due to accumulation of other genes, the Mhc evolved …more
Abstract:
Hlavný histokompatibilitný komplex (Mhc) je komplexný región, zahrňujúci množstvo génov s rozličnými funkciami. Mhc bol síce najprv určený ako dôležitý transplantačný faktor, ale neskôr bola zistená jeho úloha v prezentácii antigénnych peptidov imunitnému systému. Túto funkciu majú v Mhc len lokusy tried I a II. Vďaka akumulácii ostatných génov sa Mhc vyvinul v komplex ovplyvňujúci mnohé iné funkcie …more
 

Keywords

hlavný histokompatibilitný complex evolúcia antigénne peptidy imunitný systém stavovce ochorenia major histocompatibility complex evolution antigenic peptides immune system vertebrates diseases
 
Language used: Slovak
Date on which the thesis was submitted / produced: 13. 5. 2010
Identifier: https://is.muni.cz/th/b4r10/

Thesis defence

  • Date of defence: 18. 6. 2010
  • Supervisor: prof. MVDr. RNDr. Petr Hořín, CSc.

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta
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Masaryk University

Faculty of Science

Bachelor programme / field:
Biology / Cellular and Molecular Diagnostics

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