Action at a Distance in Arginine Repressor and the Store-operated Calcium Channel Orai: Molecular Modeling and Simulations – Saurabh Kumar PANDEY, MSc.
Saurabh Kumar PANDEY, MSc.
Doctoral thesis
Action at a Distance in Arginine Repressor and the Store-operated Calcium Channel Orai: Molecular Modeling and Simulations
Abstract:
In this thesis molecular modeling tools have been applied to investigate the phenomenon of allostery in two systems: Arginine repressor and human Orai channel. Arginine repressor protein binds to DNA in response to the intracellular concentration of L-arginine and controls the arginine metabolism in bacteria. Using molecular dynamics simulations sampling of the conformational space of arginine repressor …moreAbstract:
In this thesis molecular modeling tools have been applied to investigate the phenomenon of allostery in two systems: Arginine repressor and human Orai channel. Arginine repressor protein binds to DNA in response to the intracellular concentration of L-arginine and controls the arginine metabolism in bacteria. Using molecular dynamics simulations sampling of the conformational space of arginine repressor …more
Language used: Czech
Date on which the thesis was submitted / produced: 11. 9. 2018
Thesis defence
- Date of defence: 10. 12. 2018
- Supervisor: prof. RNDr. H. Rüdiger Ettrich, Ph.D.
Citation record
ISO 690-compliant citation record:
PANDEY, Saurabh Kumar. \textit{Action at a Distance in Arginine Repressor and the Store-operated Calcium Channel Orai: Molecular Modeling and Simulations}. Online. Doctoral theses, Dissertations. České Budějovice: University of South Bohemia in České Budějovice, Faculty of Science. 2018. Available from: https://theses.cz/id/5sk1wr/.
The right form of listing the thesis as a source quoted
PANDEY, Saurabh Kumar. Action at a Distance in Arginine Repressor and the Store-operated Calcium Channel Orai: Molecular Modeling and Simulations. N. Hrady, 2018. disertační práce (Ph.D.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
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Institution archiving the thesis and making it accessible: JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH, Přírodovědecká fakultaUNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE
Faculty of ScienceDoctoral programme / field:
Biophysics / Biophysics
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