Bc. Ján Boroň
Master's thesis
Studium interakce proteinů s telomerovou DNA
Study of interactions between proteins and telomeric DNA
Abstract:
The ends of linear chromosomes - telomeres are protected by specific protein complexes which bind telomeric ¬DNA. The human teleomere binding complex consisting of six proteins is called shelterin. Protein TIN2 has central position in shelterin complex. Protein TIN2 participates in three pivotal interactions within shelterin protein complex, which makes this protein primary target for detailed studies …moreAbstract:
Konce lineárnych chromozómov, nazývané teloméry, sú chránené špecifickými proteinovými komplexami naviazanými na telomerickou úseky DNA. U človeka sa tento komplex šiestich proteinov označuje ako shelterin. Proteín TIN2 ma ústredne postavenie v shelterinovom komplexe, kde sa účastní na troch väzbách, čo ho robí primárním cieľom pre podrobnejšie skúmanie k objasneniu stavby komplexu. V rámci tejto práce …more
Language used: Slovak
Date on which the thesis was submitted / produced: 17. 5. 2010
Identifier:
https://is.muni.cz/th/hd3ui/
Thesis defence
- Date of defence: 10. 2. 2011
- Supervisor: doc. Mgr. Ctirad Hofr, Ph.D.
Full text of thesis
Contents of on-line thesis archive
Published in Theses:- světu
Other ways of accessing the text
Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakultaMasaryk University
Faculty of ScienceMaster programme / field:
Biology / Molecular Biology and Genetics