Evaluation of cellulose derivates for wound healing dressing

Ing. Karin NOVOTNÁ

Master's thesis

Abstract:

The main of our work is to evaluate biomaterials, cellulose derivates and conclude if they would be suitable for wound healing dressing devices. Thence it follows the aim of this master thesis. It is necessary to determine properties of sorted cellulose derivates (OK CEL, HEC, CMC). The evaluation is focused on temperature and concentration of cellulose solution influences on density, surface tension, contact angle and light absorbance. Work also determines influence of ionic concentration and pH of solution on particle size and zeta potential of cellulose solutions. From our measurement we can conclude that density and surface tension of solutions depend on solution temperature and solution concentration. And the dependence for contact angle is fractional. The UV VIS spectroscopy determined that absorbance depends on solution concentration. Ions and pH of solution markedly influence only the light absorbance for OK CEL. The particle size varies by influence of varying pH of solutions or ionic concentration. The zeta potential is almost negative for determined pH range for our samples and that adding of ions does not influence this behaviour.

Abstract:

The main of our work is to evaluate biomaterials, cellulose derivates and conclude if they would be suitable for wound healing dressing devices. Thence it follows the aim of this master thesis. It is necessary to determine properties of sorted cellulose derivates (OK CEL, HEC, CMC). The evaluation is focused on temperature and concentration of cellulose solution influences on density, surface tension, contact angle and light absorbance. Work also determines influence of ionic concentration and pH of solution on particle size and zeta potential of cellulose solutions. From our measurement we can conclude that density and surface tension of solutions depend on solution temperature and solution concentration. And the dependence for contact angle is fractional. The UV VIS spectroscopy determined that absorbance depends on solution concentration. Ions and pH of solution markedly influence only the light absorbance for OK CEL. The particle size varies by influence of varying pH of solutions or ionic concentration. The zeta potential is almost negative for determined pH range for our samples and that adding of ions does not influence this behaviour.

Keywords

wound healing, cellulose derivates, surface tension, contact angle, uv-vis absorbance, particle diameter, zeta potential

Language used: English

Date on which the thesis was submitted / produced: 31. 5. 2005

Accessible from:: 29. 5. 2015

Identifier: 1955

Thesis defence

• Date of defence: 14. 6. 2005

Tomas Bata University in Zlín

Faculty of Technology

Master programme / field:
Chemistry and materials technology / Material engineering