Biochemical analysis of Orai1 mutants derived from a cancer database – Bahareh ATTAR
Bahareh ATTAR
Bachelor's thesis
Biochemical analysis of Orai1 mutants derived from a cancer database
Biochemical analysis of Orai1 mutants derived from a cancer database
Abstract:
The objective of this study involves employing PyMOL, along with pertinent references, to explore the chemiluminescence detection mechanism of membranes featuring the H134A+R91C mutation and the R91C mutation in humans. This investigation extends to a comparative analysis with the closed-channel 4HKS(K163W) mutation observed in Drosophila melanogaster, which shares similarities with the R91W mutation …moreAbstract:
This thesis examines Orai 1 mutants in cancer using chemichulation detection. It studies human-specific mutations and compares them to Drosophila melanogaster mutations. Pymol is used to visualize structural variations. The research aims to understand the molecular mechanisms of Orai 1 in cancer, potentially guiding the development of targeted cancer therapies.The objective of this study involves employing …more
Language used: English
Date on which the thesis was submitted / produced: 31. 8. 2023
Thesis defence
- Supervisor: prof. Dr. Christoph Romain
Citation record
ISO 690-compliant citation record:
ATTAR, Bahareh. \textit{Biochemical analysis of Orai1 mutants derived from a cancer database}. Online. Bachelor's thesis. České Budějovice: University of South Bohemia in České Budějovice, Faculty of Science. 2023. Available from: https://theses.cz/id/aacntf/.
The right form of listing the thesis as a source quoted
ATTAR, Bahareh. Biochemical analysis of Orai1 mutants derived from a cancer database. České Budějovice, 2023. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
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Institution archiving the thesis and making it accessible: JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH, Přírodovědecká fakultaUNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE
Faculty of ScienceBachelor programme / field:
Applied Informatics / Bioinformatics
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