Calcium signalling and gene regulation by carcinogenic Orai mutants – Bc. Monika LITVIŇUKOVÁ, BSc
Bc. Monika LITVIŇUKOVÁ, BSc
Master's thesis
Calcium signalling and gene regulation by carcinogenic Orai mutants
Abstract:
The main objective of this work is to define and characterize point mutations of the calcium channel Orai isolated form the large scale cancer genomic dataset. Those mutats were examined in the means of sub-cellular localization as well as functionality. Out of 17 investigated mutations, 5 were found to alter protein gating and switch the channel to partially or fully open state. Altered gating then …more
Language used: English
Date on which the thesis was submitted / produced: 23. 12. 2016
Thesis defence
- Supervisor: Dr. Rainer Schindl
Citation record
ISO 690-compliant citation record:
LITVIŇUKOVÁ, Monika. \textit{Calcium signalling and gene regulation by carcinogenic Orai mutants}. Online. Master's thesis. České Budějovice: University of South Bohemia in České Budějovice, Faculty of Science. 2016. Available from: https://theses.cz/id/exzn2f/.
The right form of listing the thesis as a source quoted
LITVIŇUKOVÁ, Monika. Calcium signalling and gene regulation by carcinogenic Orai mutants. Č. Budějovice, 2016. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Full text of thesis
Contents of on-line thesis archive
Published in Theses:- světu
Other ways of accessing the text
Institution archiving the thesis and making it accessible: JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH, Přírodovědecká fakultaUNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE
Faculty of ScienceMaster programme / field:
Biochemistry / Biological chemistry
Theses on a related topic
- No theses on a related topic available.
Name
Posted by
Uploaded/Created
Rights