Computational Workflow for Genome-Scale Metabolic Model Reconstruction of Non-Model Organisms – Bc. Kryštof Matuštík
Bc. Kryštof Matuštík
Bachelor's thesis
Computational Workflow for Genome-Scale Metabolic Model Reconstruction of Non-Model Organisms
Computational Workflow for Genome-Scale Metabolic Model Reconstruction of Non-Model Organisms
Abstract:
Celogenomové metabolické modely (GEM) nabízejí kolekci znalostí pro pochopení metabolických sítí specifických pro daný organismus, přičemž jejich využití sahá od strain engineering až po předpovídání chování buněk. V posledních dvou desetiletích bylo vytvořeno několik GEM, avšak vytvoření takových modelů pro nemodelové organismy je stále náročné. Tato práce představuje klíčové koncepty rekonstrukce …moreAbstract:
Genome-scale metabolic models (GEMs) offer an organism-specific knowledge base for understanding metabolic networks, with applications ranging from strain engineering to predicting cell behaviour. In the last two decades, multiple GEMs were created. However, the creation of such models for non-model organisms is still a challenging endeavour. This thesis introduces GEM reconstruction's key concepts …more
Language used: English
Date on which the thesis was submitted / produced: 23. 5. 2025
Identifier:
https://is.muni.cz/th/evt6c/
Thesis defence
- Date of defence: 26. 6. 2025
- Supervisor: doc. RNDr. David Šafránek, Ph.D.
- Reader: doc. Mgr. Ing Karel Sedlář, Ph.D.
Citation record
ISO 690-compliant citation record:
MATUŠTÍK, Kryštof. \textit{Computational Workflow for Genome-Scale Metabolic Model Reconstruction of Non-Model Organisms}. Online. Bachelor's thesis. Brno: Masaryk University, Faculty of Informatics. 2025. Available from: https://theses.cz/id/eyn5tk/.
Full text of thesis
Contents of on-line thesis archive
Published in Theses:- světu
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Institution archiving the thesis and making it accessible: Masarykova univerzita, Fakulta informatikyMasaryk University
Faculty of InformaticsBachelor programme / field:
Informatics / Informatics
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