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Bc. Pavel STEFFAL

Master's thesis

Studium senzitivity signální dráhy přes receptor Notch na aminokyseliny v potravě

Abstract:
The sensitivity of Notch signaling pathway to metabolism has been proposed in several recent studies but it is unclear if the changes in fly diet composition can directly lead to changes in Notch phenotype in vivo. In this work we show that activity of Notch pathway is sensitive to amino acids via the TOR pathway. In addition we will test a candidate protein as a sensor for amino acid level in the …more
Abstract:
The sensitivity of Notch signaling pathway to metabolism has been proposed in several recent studies but it is unclear if the changes in fly diet composition can directly lead to changes in Notch phenotype in vivo. In this work we show that activity of Notch pathway is sensitive to amino acids via the TOR pathway. In addition we will test a candidate protein as a sensor for amino acid level in the …more
 

Keywords

Notch aminoacids metabolism TOR
 
Language used: Czech
Date on which the thesis was submitted / produced: 16. 4. 2018

Thesis defence

  • Supervisor: RNDr. Alena Bruce, Ph.D.

Citation record

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STEFFAL, Pavel. Studium senzitivity signální dráhy přes receptor Notch na aminokyseliny v potravě. Č. Budějovice, 2018. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

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