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RNDr. Ivana Beššeová, Ph.D.

Master's thesis

Počítačové studium ribizomální RNA

Computational study of the ribosomal RNA
Abstract:
Práca sa zaoberá štúdiom ribozomálneho motívu three-way junction) z Haloarcula marimortui (ribozomálnych helixov 90-92pomocou teoretických výpočtových metód molekulovej dynamiky a kvantovej chémie. Cieľom práce bolo, pomocou molekulovo dynamických simulácií (463ns), charakterizovanie štruktúrnych zmien a dynamiky junction a správanie sa rezidua U2587, hrajúce dôležitú rolu pri akomodácií tRNA v A-mieste …more
Abstract:
The diploma thesis is focused on the ribosomal three-way junction motif from Haloarcula marimortui (ribosomal helices 90-92) utilizing modern molecular dynamics methods. The objective of the diploma thesis was to characterize structural changes and dynamics of junction and residue U2587 that plays key role in accommodation of the tRNA in the A-site of the ribosome. The residue U2587 was investigated …more
 

Keywords

ribozóm A-loop junction molekulární dynamika ribosome molecular dynamics
 
Language used: Czech
Date on which the thesis was submitted / produced: 21. 6. 2007
Identifier: https://is.muni.cz/th/mii38/

Thesis defence

  • Date of defence: 7. 6. 2007
  • Supervisor: prof. RNDr. Jiří Šponer, DrSc.

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta
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