Characterization of pore opening relevant residues in TM3 and TM4 domains of Orai1 – Bc. Ana-Marija ANDOVA, BSc
Bc. Ana-Marija ANDOVA, BSc
Master's thesis
Characterization of pore opening relevant residues in TM3 and TM4 domains of Orai1
Characterization of pore opening relevant residues in TM3 and TM4 domains of Orai1
Abstract:
Calcium (Ca2+) ions play a crucial role in almost every aspect of cellular life. The most prominent calcium entry pathway into the cell is the calcium release-activated calcium (CRAC) channel, composed of the Orai1 protein, and the stromal interaction molecule STIM1. The channel is activated through conformational changes upon STIM1 coupling to the C-terminus of Orai1 protein following store depletion …moreAbstract:
Calcium (Ca2+) ions play a crucial role in almost every aspect of cellular life. The most prominent calcium entry pathway into the cell is the calcium release-activated calcium (CRAC) channel, composed of the Orai1 protein, and the stromal interaction molecule STIM1. The channel is activated through conformational changes upon STIM1 coupling to the C-terminus of Orai1 protein following store depletion …more
Language used: English
Date on which the thesis was submitted / produced: 15. 12. 2022
Thesis defence
- Supervisor: Dr. Isabella Derler
Citation record
ISO 690-compliant citation record:
ANDOVA, Ana-Marija. \textit{Characterization of pore opening relevant residues in TM3 and TM4 domains of Orai1}. Online. Master's thesis. České Budějovice: University of South Bohemia in České Budějovice, Faculty of Science. 2022. Available from: https://theses.cz/id/j2ngig/.
The right form of listing the thesis as a source quoted
ANDOVA, Ana-Marija. Characterization of pore opening relevant residues in TM3 and TM4 domains of Orai1. České Budějovice, 2022. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
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Institution archiving the thesis and making it accessible: JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH, Přírodovědecká fakultaUNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE
Faculty of ScienceMaster programme / field:
Biological Chemistry / Biological Chemistry
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