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Bc. David Číhal

Bachelor's thesis

Testování multivalentních inhibitorů lektinů z patogenů

Testing multivalent inhibitors of lectins from pathogens
Abstract:
Cílem této bakalářské práce bylo otestovat nově syntetizované multivalentní inhibitory lektinu PA-IIL produkovaného oportunním lidským patogenem Pseudomonas aeruginosa. Metodami zkoumání byly hemaglutinace a její inhibice. Schopnost lektinu PA-IIL aglutinovat erytrocyty byla ověřena hemaglutinací erytrocytů tří krevních skupin A, B a 0 ošetřených i neošetřených papainem. Lektin byl schopen aglutinovat …more
Abstract:
Aim of this bachelor thesis was to test newly synthesised multivalent inhibitors of lectin PA-IIL produced by the opportunistic human pathogen Pseudomonas aeruginosa. Hemagglutination and its inhibition were methods of the research. The ability of the lectin PA IIL to hemagglutinate erythrocytes was verified by hemagglutination of erythrocytes of three blood groups A, B and 0, treated and untreated …more
 

Keywords

inhibitors Pseudomonas aeruginosa lectin hemagglutination PA-IIL inhibitory lektin hemaglutinace
 
Language used: Czech
Date on which the thesis was submitted / produced: 1. 6. 2021
Identifier: https://is.muni.cz/th/nfnq8/

Thesis defence

  • Date of defence: 7. 7. 2021
  • Supervisor: Mgr. Lenka Malinovská, Ph.D., prof. RNDr. Michaela Wimmerová, Ph.D.
  • Reader: MVDr. Eva Fujdiarová, Ph.D.

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta
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Masaryk University

Faculty of Science

Bachelor programme / field:
Biochemistry / Biochemistry

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