Screening Cyanobacteria for Apoptosis Induction in Human Cancer Cell Lines: Discovery of a Novel Compound Nocuolin A – Mgr. Kateřina VORÁČOVÁ
Mgr. Kateřina VORÁČOVÁ
Doctoral thesis
Screening Cyanobacteria for Apoptosis Induction in Human Cancer Cell Lines: Discovery of a Novel Compound Nocuolin A
Abstract:
Cancer-related diseases are mostly associated with reduced or inappropriate cell death. This thesis focuses on secondary cyanobacterial metabolites which induce apoptosis in human cancer cells in vitro and thus may serve as potential drug hits. Screening and selection of active natural extracts clearly precede activity-guided isolation of a bioactive compound itself. Summarizing the results of phenotypic …moreAbstract:
Cancer-related diseases are mostly associated with reduced or inappropriate cell death. This thesis focuses on secondary cyanobacterial metabolites which induce apoptosis in human cancer cells in vitro and thus may serve as potential drug hits. Screening and selection of active natural extracts clearly precede activity-guided isolation of a bioactive compound itself. Summarizing the results of phenotypic …more
Language used: English
Date on which the thesis was submitted / produced: 10. 6. 2017
Thesis defence
- Supervisor: Mgr. Pavel Hrouzek
Citation record
ISO 690-compliant citation record:
VORÁČOVÁ, Kateřina. \textit{Screening Cyanobacteria for Apoptosis Induction in Human Cancer Cell Lines: Discovery of a Novel Compound Nocuolin A}. Online. Doctoral theses, Dissertations. České Budějovice: University of South Bohemia in České Budějovice, Faculty of Science. 2017. Available from: https://theses.cz/id/jh7ov7/.
The right form of listing the thesis as a source quoted
VORÁČOVÁ, Kateřina. Screening Cyanobacteria for Apoptosis Induction in Human Cancer Cell Lines: Discovery of a Novel Compound Nocuolin A . Č. Budějovice, 2017. disertační práce (Ph.D.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Full text of thesis
Contents of on-line thesis archive
Published in Theses:- světu
Other ways of accessing the text
Institution archiving the thesis and making it accessible: JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH, Přírodovědecká fakultaUNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE
Faculty of ScienceDoctoral programme / field:
Molecular and Cell Biology / Molecular and Cell Biology and Genetics
Theses on a related topic
-
Secondary metabolites of terrestrial cyanobacteria
Aleksandra KAPUŚCIK -
Polyphasic analysis and secondary metabolite patterns in unbranched heterocytous cyanobacteria with different life strategies
Andreja KUST -
Influence of cultivation conditions and age of the culture on the production of cytostatic secondary metabolite 2505 and its natural analogues
Zuzana GAJARSKÁ
Name
Posted by
Uploaded/Created
Rights