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MUDr. Milan Matuška, Ph.D.

Doctoral thesis

Chemoterapií indukovaná neutropenie u pacientů s Hodgkinovým lymfomem

Chemotherapy - related neutropenia in patients with Hodgkins lymphoma
Abstract:
Hlavním cílem studie bylo porovnat akutní hematologickou toxicitu standardních chemoterapeutických režimů COPP/ABVD, ABVD s intenzifikovaným režimem BEACOPP v jeho bazální (baz) i eskalované (esk)variantě. Vedlejšími cíli bylo posouzení četnosti infekcí, efektu epoetinu alfa (EPO)na snížení počtu transfúzí a dodržení dávkové intenzity u režimu BEACOPP esk.
Abstract:
We compared chemotherapy regimens COPP/ABVD or ABVD vs BEACOPP baseline (bas) or BEACOPP escalated (esc) as initial chemotherapy for Hodgkins disease. The major end points were chemotherapy-related neutropenia, infection, effects of erythropoietin (EPO) on reductions in the number of transfusions, dose reductions of planned therapy BEACOPP esc.
 

Keywords

Hodgkinův lymfom chemoterapie neutropenie erytropoetin Hodgkins lymphoma chemotherapy neutropenia erythropoietin
 
Language used: Czech
Date on which the thesis was submitted / produced: 9. 5. 2006
Identifier: https://is.muni.cz/th/rukk1/

Thesis defence

  • Date of defence: 20. 6. 2006
  • Supervisor: prof. MUDr. Jiří Vorlíček, CSc.

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Lékařská fakulta
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Masaryk University

Faculty of Medicine

Doctoral programme / field:
General Medicine / Oncology

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