Zpět na vyhledávání

PharmDr. Gabriela Škovranová, Ph.D.

Doctoral thesis

Přírodní prenylované fenoly jako antimikrobiální látky

Natural prenylated phenolics as antimicrobial agents
Abstract:
Antimikrobiálna rezistencia je celosvetovou hrozbou, preto je veľmi žiaduce hľadať nové terapeutické prístupy. Predmetom nášho skúmania boli prenylované fenoly z kôry koreňa Morus alba L. a z plodov Paulownia tomentosa (Thunb.) Steud. Antimikrobiálne vlastnosti voči Staphylococcus aureus sme popísali pri ich použití samostatne a tiež v kombinácii s antibiotikami. Medzi spôsoby, ktoré prenylované fenoly …more
Abstract:
Antimicrobial resistance is a global threat, and searching for new therapeutic approaches is demanding. Thus, prenylated phenolics from the root bark of Morus alba L. and fruits of Paulownia tomentosa (Thunb.) Steud. were investigated. Their antimicrobial properties against Staphylococcus aureus alone and in combination with antibiotics were described. Membrane disruption of bacteria, efflux pump inhibition …more
 

Keywords

antimikrobiálna aktivita hojenie rán Morus alba Paulownia tomentosa prenylované fenoly quorum sensing inhibícia synergia antimicrobial activity prenylated phenolics quorum sensing inhibition synergy wound healing
 
Language used: English
Date on which the thesis was submitted / produced: 29. 1. 2024
Identifier: https://is.muni.cz/th/e1haf/

Thesis defence

  • Date of defence: 4. 4. 2024
  • Supervisor: PharmDr. Alice Sychrová, Ph.D.
  • Reader: doc. Ing. Ladislav Kokoška, Ph.D., prof. Mag. Dr.rer.nat. Franz Bucar, prof. Adam Matkowski

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Farmaceutická fakulta
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Masaryk University

Faculty of Pharmacy

Doctoral programme / field:
Pharmacognosy / Pharmacognosy

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