Software using random forest for risk prediction of heart valve surgery patients

Georg HERMANUTZ

Bakalářská práce

Abstract:

CASPeR - Cardiac surgery prediction tool for risk stratification of heart valve surgeries is presented. The base builds a machine learning pipeline for training a random forest classifier which predicts the mortality after a certain amount of days after the surgery was performed. The classifier also offers a list of potential risk factors through its in build feature selection. With a survival analysis the groups "high-risk" and "low-risk" are compared with each other to check for statistical difference. The tool uses "Shiny" a R package which offers a web frame work to develop data analysis visualizations for the User Interface. CASpeR is delivered as a Microsoft Windows standalone desktop application, that comes with a .exe installer and a detailed manual.

Abstract:

CASPeR - Cardiac surgery prediction tool for risk stratification of heart valve surgeries is presented. The base builds a machine learning pipeline for training a random forest classifier which predicts the mortality after a certain amount of days after the surgery was performed. The classifier also offers a list of potential risk factors through its in build feature selection. With a survival analysis the groups "high-risk" and "low-risk" are compared with each other to check for statistical difference. The tool uses "Shiny" a R package which offers a web frame work to develop data analysis visualizations for the User Interface. CASpeR is delivered as a Microsoft Windows standalone desktop application, that comes with a .exe installer and a detailed manual.

Keywords

R, machine learning, random forest, Shiny, survival analysis, Kaplan-Meier estimator, heart valve surgery, euroSCORE, prediction, predictive medicine

Jazyk práce: angličtina

Datum vytvoření / odevzdání či podání práce: 21. 7. 2017

Obhajoba závěrečné práce

• Vedoucí: doc. Dr. Ulrich Bodenhofer

JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH

Přírodovědecká fakulta

Bakalářský studijní program / obor:
Applied Informatics / Bioinformatics