Crossroads of genetics and epigenetics: nucleosome assembly and chromosome integrity – Mgr. Karin Jaške, Ph.D.
Mgr. Karin Jaške, Ph.D.
Doctoral thesis
Crossroads of genetics and epigenetics: nucleosome assembly and chromosome integrity
Crossroads of genetics and epigenetics: nucleosome assembly and chromosome integrity
Abstract:
Genetika s epigenetikou se protínají v momentě realizace informace obsažené v genomu. Exprese a opravy DNA jsou determinovány nukleoproteinovou strukturou chromatinu. Sestavování nukleozomů jako základních podjednotek chromatinu je v eukaryotických organismech zajištěno specifickými komplexy proteinů, mezi které patří Chromatin Assembly Factor 1 (CAF1) hrající klíčovou roli v nakládání histonů na vlákno …moreAbstract:
Genetics and epigenetics come across at the moment of the realization of information encoded in the genome. DNA expression and repair are influenced and conditioned by nucleoprotein chromatin structure. Assembly of the nucleosome as the basic unit of chromatin in eukaryotic organisms is guided by special protein complexes and one of them is the Chromatin Assembly Factor 1 (CAF1) playing a crucial role …more
Language used: English
Date on which the thesis was submitted / produced: 4. 4. 2017
Identifier:
https://is.muni.cz/th/laaa5/
Thesis defence
- Date of defence: 4. 5. 2017
- Supervisor: doc. Mgr. Miloslava Fojtová, CSc.
- Reader: RNDr. Karel Angelis, CSc., RNDr. Roman Hobza, Ph.D.
Citation record
ISO 690-compliant citation record:
JAŠKE, Karin. \textit{Crossroads of genetics and epigenetics: nucleosome assembly and chromosome integrity}. Online. Doctoral theses, Dissertations. Brno: Masaryk University, Faculty of Science. 2017. Available from: https://theses.cz/id/q3mp32/.
Full text of thesis
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Published in Theses:- světu
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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakultaMasaryk University
Faculty of ScienceDoctoral programme / field:
Biochemistry (4-years) / Genomics and Proteomics
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