Bc. Diana Bartáková

Master's thesis

Nové elektrochemické přístupy v molekulární onkologii

Novel electrochemical approaches in molecular oncology
Abstract:
This diploma thesis deals with electrochemical analysis of nucleic acids and its application to molecular oncology. The diploma thesis aims to develop a method for detecting microRNA, short RNA molecules, which exhibit changed levels in tumors and could therefore serve as potential biomarkers. Another topic is electrochemical differentiation of methylated and unmethylated DNA, since tumor cells were …more
Abstract:
Táto diplomová práca sa zaoberá elektrochemickou analýzou nukleových kyselín a jej aplikáciou do molekulárnej onkológie. Konkrétne ide o vývoj metódy na detekciu mikroRNA, krátkych RNA molekúl, u ktorých sa zistila zmenená hladina v nádoroch, a preto môžu slúžiť ako potenciálne biomarkery. Ďalšou témou je elektrochemické rozlíšenie metylovanej a nemetylovanej DNA, keďže v nádorových bunkách boli objavené …more
 
 
Language used: Slovak
Date on which the thesis was submitted / produced: 4. 1. 2018

Thesis defence

  • Date of defence: 14. 2. 2018
  • Supervisor: Mgr. Martin Bartošík, Ph.D.
  • Reader: doc. Mgr. Václav Brázda, Ph.D.

Citation record

Full text of thesis

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta

Masaryk University

Faculty of Science

Master programme / field:
Biochemistry / Biochemistry

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