Bc. Juraj Polaček

Bachelor's thesis

Aktivátory NF-kappaB dráhy RNF25 a TRAF3IP2 a jejich úloha v metastazování nádorů

NF-kappaB activators RNF25 and TRAF3IP2 and their role in tumor metastasis
Abstract:
This bachelor thesis is focused on the effect of Ring Finger Protein 25 (RNF25) and TRAF3 interacting protein2 (TRAF3IP2) protein expression on viscoelastic properties of tumor cell line MCF-7, derived from breast cancer tissue. Theoretical part describes functions and structure of these NF-kappaB activating proteins, and principles of atomic force microscopy. In experimental part of the thesis, we …more
Abstract:
Táto bakalárska práca je zameraná na vplyv expresie proteínov Ring Finger Protein 25 (RNF25) a TRAF3 interacting protein2 (TRAF3IP2) na viskoelastické vlastnosti nádorovej bunkovej línie MCF-7, odvodenej od nádoru prsníka ženy. Teoretická časť zahŕňa opis štruktúry a funkcie NF-kappaB aktivujúcich proteínov a princíp metódy mikroskopie atómových síl. V experimentálnej časti práce sme pomocou AFM zistili …more
 
 
Language used: Slovak
Date on which the thesis was submitted / produced: 18. 5. 2018

Thesis defence

  • Date of defence: 12. 6. 2018
  • Supervisor: doc. Mgr. Pavel Bouchal, Ph.D.
  • Reader: Mgr. Josef Maryáš

Citation record

Full text of thesis

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta