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Bc. Zuzana Bertová

Master's thesis

Studium biomechaniky buněk s použitím AFM nanoindentace

Cell biomechanics sutdied by AFM nanoindentation
Abstract:
This diploma thesis deals with the study of cell stiffness characterized by Young’s modulus of tumor cell line MCF7 using the AFM nanoindentation method. The effect of probe tip geometry and the relative force setpoint on the Young's modulus obtained was analyzed. The obtained force curves were processed in different evaluation software and using different fit models. After the measurement was optimized …more
Abstract:
Táto diplomová práca sa zaoberá štúdiom tuhosti buniek charakterizovanej Youngovým modulom pružnosti nádorovej bunkovej línie MCF7 pomocou metódy AFM nanoindentácie. Bol analyzovaný vplyv geometrie hrotu próby a veľkosti maximálnej pôsobiacej sily v meraní na získané hodnoty Youngovho modulu pružnosti. Získané silové krivky boli spracované v rôznych vyhodnocovacích softvéroch a za použitia rozličných …more
 

Keywords

AFM mikroskopie atomárních sil nanoindentace rakovina prsu MCF7 Youngův modul pružnosti tuhost AtomicJ mikroskopia atomárnych síl nanoindentácia rakovina prsníku Youngov modul pružnosti atomic force microscopy nanoindentation breast cancer Young’s modulus stiffness
 
Language used: Slovak
Date on which the thesis was submitted / produced: 15. 5. 2019
Identifier: https://is.muni.cz/th/vu5mh/

Thesis defence

  • Date of defence: 6. 6. 2019
  • Supervisor: Mgr. Jan Přibyl, Ph.D.

Citation record

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta
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