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Bc. et Bc. Nora MÜLLER

Master's thesis

Unnatural amino acids as tool to study protein interaction

Unnatural amino acids as tool to study protein interaction
Abstract:
In this study, we investigate several gating loci present in the transmembrane region TM3 (L174, A177, V181, L185, F187, L188, V192) and TM4 (A254) of Orai1. These gating loci are known to alter the Orai1 channel activity upon conventional mutagenesis. The aim of the thesis was to incorporate proximity-dependent photocrosslinking unnatural amino acids (UAAs) p-azido-L-phenylalanine (Azi) and p-benzoyl …more
 
 
Language used: English
Date on which the thesis was submitted / produced: 2. 5. 2023

Thesis defence

  • Supervisor: Dr. Isabella Derler

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MÜLLER, Nora. Unnatural amino acids as tool to study protein interaction. České Budějovice, 2023. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta

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  • Soubory jsou nedostupné do 2. 5. 2026
  • Po tomto datu bude práce dostupná: světu
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UNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE

Faculty of Science

Master programme / field:
Biological Chemistry / Biological Chemistry

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