Bc. Kateřina Sejpková

Master's thesis

Vliv stilbenů na zánětlivou odpověď endoteliálních buněk in vitro

Stilbenes and their influence on the endothelial inflammatory response in vitro
Abstract:
Lipopolysacharid (LPS) z Escherichia coli indukuje obrannou imunitní reakci prostřednictvím Toll-like receptoru 4 (TLR4), který je členem rodiny vrozených imunitních receptorů rozpoznávajících molekuly asociované s patogeny (pathogene associated molecular patterns, PAMP) a molekuly související s rozvojem stresové reakce (dangerous associated molecular patterns, DAMP). Předpokládali jsme, že stilbeny …more
Abstract:
Escherichia coli lipopolysaccharide (LPS) induces proinflammatory processes via Toll-like receptor 4 (TLR4), a member of innate immunity receptor family recognizing pathogene associated molecular patterns (PAMP) and dangerous associated molecular patterns (DAMP). Stilbenes resveratrol, pterostilbene and pinosylvin were hypothesized to be able to decrease LPS-induced activation of TLR4 signalling pathway …more
 
 
Language used: Czech
Date on which the thesis was submitted / produced: 11. 5. 2015

Thesis defence

  • Date of defence: 3. 6. 2015
  • Supervisor: RNDr. Lenka Švihálková Šindlerová, Ph.D.

Citation record

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