Fibroblast signaling pathways in regulation of mammary gland morphogenesis – MUDr. Jakub Sumbal
MUDr. Jakub Sumbal
Doctoral thesis
Fibroblast signaling pathways in regulation of mammary gland morphogenesis
Fibroblast signaling pathways in regulation of mammary gland morphogenesis
Abstract:
Tato práce je zaměřena na fibroblasty, buňky mezenchymu/stromatu, a jejich roli při větvící morfogenezi epitelu. Hlavní část práce tvoří dva články, z nichž jeden je opublikován a jeden v recenzním řízení. První studie popisuje funkční úlohu fibroblastů na větvící morfogenezi mléčné žlázy v systému kokultur in vitro a identifikuje kontraktilitu fibroblastů jako nový faktor ovlivňující větvení mléčné …moreAbstract:
This thesis is focused on fibroblasts, cells of the mesenchyme/stroma, and their role during epithelial branching morphogenesis. The body of the thesis is composed of two manuscripts that are published and under review. The first study describes the functional role of fibroblasts in mammary gland branching morphogenesis in co-culture system in vitro, identifying fibroblast contractility as a novel …more
Language used: English
Date on which the thesis was submitted / produced: 15. 8. 2024
Identifier:
https://is.muni.cz/th/lnn4o/
Thesis defence
- Date of defence: 20. 9. 2024
- Supervisor: doc. MVDr. Aleš Hampl, CSc.
- Reader: Associate Professor Mariaceleste Aragona, PhD, Colinda Scheele
Citation record
ISO 690-compliant citation record:
SUMBAL, Jakub. \textit{Fibroblast signaling pathways in regulation of mammary gland morphogenesis}. Online. Doctoral theses, Dissertations. Brno: Masaryk University, Faculty of Medicine. 2024. Available from: https://theses.cz/id/x99x2x/.
Full text of thesis
Contents of on-line thesis archive
Published in Theses:- světu
Other ways of accessing the text
Institution archiving the thesis and making it accessible: Masarykova univerzita, Lékařská fakultaMasaryk University
Faculty of MedicineDoctoral programme / field:
Biomedical sciences / Cell and Tissue Morphology