Design a syntéza nerapalogových alosterických inhibitorů mTOR – Jan Gebrt
Jan Gebrt
Bachelor's thesis
Design a syntéza nerapalogových alosterických inhibitorů mTOR
Design and synthesis of non-rapalog allosteric mTOR inhibitors
Abstract:
The Bachelor Thesis focuses on the design and synthesis of substances derived from the compound WRX606 that belongs to the group of so-called non-rapalog inhibitors of mTOR protein complex (mechanistic target of rapamycin) which affects a broad spectrum of signaling pathways in the human body. Dysregulated activity of this complex results in undesirable changes in mentioned cascades leading to the …more
Language used: English
Date on which the thesis was submitted / produced: 9. 5. 2023
Identifier:
http://evskp.uhk.cz/eB14308
Thesis defence
- Date of defence: 6. 6. 2023
- Supervisor: Mgr. Eugenie Nepovimová, Ph.D.
- Reader: RNDr. Patrik Olekšák, PhD.
Citation record
Full text of thesis
Contents of on-line thesis archive
Published in Theses:- Soubory jsou nedostupné do 30. 6. 2026
- Po tomto datu bude práce dostupná: světu
Other ways of accessing the text
Institution archiving the thesis and making it accessible: Univerzita Hradec KrálovéUniversity of Hradec Králové
Faculty of ScienceBachelor programme / field:
Chemie / Toxikologie a analýza škodlivin