Metabolic and protein biomarkers associated with gut microbiota – Anne-Christine Aust, M.Sc.
Anne-Christine Aust, M.Sc.
Doctoral thesis
Metabolic and protein biomarkers associated with gut microbiota
Metabolic and protein biomarkers associated with gut microbiota
Abstract:
Vnější faktory, včetně způsobu porodu a použití antibiotik, ovlivňují rozvoj mikrobioty u novorozenců a novorozenců a profil produkovaných metabolitů. Bakteriální mikroflóra a její metabolity modulují rozvoj imunitního systému a podporují slizniční integritu. Metabolity tryptofanu (TRP) jsou důležité pro regulaci střevní homeostázy i pro ochranu neuronů před oxidativním stresem. Tato práce se zaměřuje …moreAbstract:
Environmental factors such as the mode of birth and antibiotics impact the microbiota and its produced metabolites in a newborn child. The produced bacterial metabolites modulate the infant’s immune system and support mucosal homeostasis. Tryptophan (TRP) metabolites regulate intestinal gut homeostasis and protect neurons against oxidative stress. This thesis investigates the infant’s tryptophan metabolites …more
Language used: English
Date on which the thesis was submitted / produced: 29. 3. 2023
Identifier:
https://is.muni.cz/th/mtd5z/
Thesis defence
- Date of defence: 18. 5. 2023
- Supervisor: PharmDr. Zdeněk Spáčil, Ph.D.
- Reader: prof. Ing. Josef Čáslavský, CSc., prof. MUDr. Mgr. Milan Raška, Ph.D.
Citation record
ISO 690-compliant citation record:
AUST, Anne-Christine. \textit{Metabolic and protein biomarkers associated with gut microbiota}. Online. Doctoral theses, Dissertations. Brno: Masaryk University, Faculty of Science. 2023. Available from: https://theses.cz/id/xebk0c/.
Full text of thesis
Contents of on-line thesis archive
Published in Theses:- světu
Other ways of accessing the text
Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakultaMasaryk University
Faculty of ScienceDoctoral programme / field:
Environmental Health Sciences / Environmental chemistry and toxicology