MAGE (Melanoma-associated AntiGEn) proteiny: kofaktory buněčných procesů – Mgr. Lucie Bozděchová, Ph.D.
Mgr. Lucie Bozděchová, Ph.D.
Doctoral thesis
MAGE (Melanoma-associated AntiGEn) proteiny: kofaktory buněčných procesů
MAGE (Melanoma-associated AntiGEn) proteins: cofactors of cell processes
Abstract:
SMC (Structural maintenance of chormosome) komplexy jsou konzervované napříč všemi organizmy a podílejí se na organizaci a kompaktnosti chromozomů. Jsou složené z SMC proteinů a tzv. non-Smc podjednotek. Jeden z těchto komplexů, Smc5/6, obsahuje proteiny Nse1, Nse3 a Nse4, které tvoří těsný subkomplex. Savčím orthologem proteinu Nse3 je MAGEG1, člen rodiny MAGE (Melanoma-associated antigen) proteinů …moreAbstract:
The SMC (Structural maintenance of chromosome) complexes are conserved through all organisms. They are key players in chromosome structure organization and maintenance. These complexes are composed of the SMC proteins and non-Smc subunits. One of these complexes is Smc5/6 and contains Nse1, Nse3 and Nse4 subunits which form a tight subcomplex. The mammalian ortholog of Nse3 protein is MAGEG1, founding …more
Language used: Czech
Date on which the thesis was submitted / produced: 6. 9. 2016
Identifier:
https://is.muni.cz/th/rbojo/
Thesis defence
- Date of defence: 24. 10. 2016
- Supervisor: doc. Mgr. Jan Paleček, Dr. rer. nat.
- Reader: MUDr. Petr Müller, Ph.D., RNDr. Karel J. Angelis, CSc.
Citation record
ISO 690-compliant citation record:
BOZDĚCHOVÁ, Lucie. \textit{MAGE (Melanoma-associated AntiGEn) proteiny: kofaktory buněčných procesů}. Online. Doctoral theses, Dissertations. Brno: Masaryk University, Faculty of Science. 2016. Available from: https://theses.cz/id/xw9in1/.
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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakultaMasaryk University
Faculty of ScienceDoctoral programme / field:
Biochemistry (4-years) / Genomics and Proteomics
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