Benjamin SCHATZMANN
Bachelor's thesis
Immunometabolic Tumor Therapy
Immunometabolic Tumor Therapy
Abstract:
MBTA therapy (mixture of mannan-BAM, Toll-like receptor agonists and anti-CD40 antibody) is a cancer immunotherapy developed by Dr. Ženka. This thesis investigates options of MBTA therapy in combination with glutamine metabolism inhibitor 6-diazo-5-oxo-L-norleucine (DON). The dosage of DON, ways of application, and side effects on mice were investigated. Also, the option of replacing the mannan-BAM …moreAbstract:
MBTA therapy (mixture of mannan-BAM, Toll-like receptor agonists and anti-CD40 antibody) is a cancer immunotherapy developed by Dr. Ženka. This thesis investigates options of MBTA therapy in combination with glutamine metabolism inhibitor 6-diazo-5-oxo-L-norleucine (DON). The dosage of DON, ways of application, and side effects on mice were investigated. Also, the option of replacing the mannan-BAM …more
Language used: English
Date on which the thesis was submitted / produced: 1. 12. 2023
Thesis defence
- Supervisor: Mgr. Radka Lencová
Citation record
The right form of listing the thesis as a source quoted
SCHATZMANN, Benjamin. Immunometabolic Tumor Therapy . České Budějovice, 2023. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
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Institution archiving the thesis and making it accessible: JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH, Přírodovědecká fakultaUNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE
Faculty of ScienceBachelor programme / field:
Biological Chemistry / Biological Chemistry
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