Anticancer and Neuroprotective Activity of Nucleosides, Mictotubule-Targeting – RNDr. Lenka HRUBÁ
RNDr. Lenka HRUBÁ
Doctoral thesis
Anticancer and Neuroprotective Activity of Nucleosides, Mictotubule-Targeting
Anticancer and Neuroprotective Activity of Nucleosides, Mictotubule-Targeting
Abstract:
Nukleosidy jsou biologicky aktivní látky, strukturně velmi podobné nukleotidům, které jsou základními stavebními kameny nukleových kyselin. V klinické praxi nacházejí nukleosidy uplatnění jako antivirotika a protinádorová léčiva, nicméně v posledních letech se objevují další možnosti jejich klinického uplatnění. V této práci jsme se zaměřili na protinádorové účinky nukleosidů a mechanismy vzniku rezistence …moreAbstract:
Nucleosides are biologically active compounds, structurally very similar to nucleotides, of which nucleic acids are composed. In clinics, nucleosides are used as antiviral or anticancer drugs. However, the possibilities of their further application have been explored in recent years. In this dissertation thesis, we focused mainly on the anticancer activity of nucleosides and mechanisms of their drug …more
Language used: English
Date on which the thesis was submitted / produced: 12. 9. 2023
Thesis defence
- Supervisor: MUDr. Petr Džubák, Ph.D.
Citation record
ISO 690-compliant citation record:
HRUBÁ, Lenka. \textit{Anticancer and Neuroprotective Activity of Nucleosides, Mictotubule-Targeting}. Online. Doctoral theses, Dissertations. Olomouc: Palacký University Olomouc, Faculty of Medicine and Dentistry. 2023. Available from: https://theses.cz/id/zsw8vo/.
The right form of listing the thesis as a source quoted
HRUBÁ, Lenka. Anticancer and Neuroprotective Activity of Nucleosides, Mictotubule-Targeting. Olomouc, 2023. disertační práce (Ph.D.). UNIVERZITA PALACKÉHO V OLOMOUCI. Lékařská fakulta
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Institution archiving the thesis and making it accessible: UNIVERZITA PALACKÉHO V OLOMOUCI, Lékařská fakultaPalacký University Olomouc
Faculty of Medicine and DentistryDoctoral programme / field:
Pediatrics / Pediatrics
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