In silico predikce vazebných vlastností lektinu RS20L – Bc. Michal Ďurech, Ph.D.
Bc. Michal Ďurech, Ph.D.
Master's thesis
In silico predikce vazebných vlastností lektinu RS20L
In silico prediction of lectin RS20L binding properties
Abstract:
This thesis is focused on in silico prediction of binding properties of Ralstonia solanacearum lectin RS20L by means of molecular docking and molecular dynamics simulations. In lectin RS20L there were identified two types of binding sites probably with different sugar specificity. Three water molecules were found in a groove binding site which could mediate saccharide binding to the lectin structure …moreAbstract:
Táto práca bola zameraná na in silico štúdium väzbových vlastností lektínu RS20L metódou molekulárneho dokovania a simuláciou molekulovej dynamiky. Lektín obsahuje dva typy väzbových miest, ktoré sa pravdepodobne líšia v sacharidovej špecifite. V žliabkovom mieste boli identifikované tri molekuly vody, ktoré by potenciálne mohli sprostredkovať interakciu medzi lektínom a sacharidom, z ktorých dve boli …more
Language used: Slovak
Date on which the thesis was submitted / produced: 10. 5. 2011
Identifier:
https://is.muni.cz/th/bok7q/
Thesis defence
- Date of defence: 8. 6. 2011
- Supervisor: prof. RNDr. Michaela Wimmerová, Ph.D.
Citation record
Full text of thesis
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Published in Theses:- světu
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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakultaMasaryk University
Faculty of ScienceMaster programme / field:
Biochemistry / Biochemistry
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