Combination of cancer immunotherapy with inhibitors of glutamine metabolism – Konstantin KOSENKO
Konstantin KOSENKO
Bachelor's thesis
Combination of cancer immunotherapy with inhibitors of glutamine metabolism
Combination of immunotherapy with inhibitors of glutamine metabolism
Abstract:
The focus of this thesis was the combination of immunotherapy with glutamine metabolism inhibitors. Glutamine analogs such as 6-diazo-5-oxo-L-norleucine (DON) have been known for many decades; however, their use has been limited due to severe side effects. In this study, we focused on DON and its prodrug LTP607 and tested its combination with immunotherapy that includes mannan-BAM, Toll-like receptor …moreAbstract:
The focus of this thesis was the combination of immunotherapy with glutamine metabolism inhibitors. Glutamine analogs such as 6-diazo-5-oxo-L-norleucine (DON) have been known for many decades; however, their use has been limited due to severe side effects. In this study, we focused on DON and its prodrug LTP607 and tested its combination with immunotherapy that includes mannan-BAM, Toll-like receptor …more
Language used: English
Date on which the thesis was submitted / produced: 15. 12. 2022
Thesis defence
- Supervisor: RNDr. Jan Ženka, CSc.
Citation record
ISO 690-compliant citation record:
KOSENKO, Konstantin. \textit{Combination of cancer immunotherapy with inhibitors of glutamine metabolism}. Online. Bachelor's thesis. České Budějovice: University of South Bohemia in České Budějovice, Faculty of Science. 2022. Available from: https://theses.cz/id/1kf8nl/.
The right form of listing the thesis as a source quoted
KOSENKO, Konstantin. Combination of cancer immunotherapy with inhibitors of glutamine metabolism. České Budějovice, 2022. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Full text of thesis
Contents of on-line thesis archive
Published in Theses:- světu
Other ways of accessing the text
Institution archiving the thesis and making it accessible: JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH, Přírodovědecká fakultaUNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE
Faculty of ScienceBachelor programme / field:
Biological Chemistry / Biological Chemistry
Theses on a related topic
Name
Posted by
Uploaded/Created
Rights