Štúdium protinádorového účinku tomatidínu na modelu mamárneho karcinómu – Bc. Anna Lierová
Bc. Anna Lierová
Master's thesis
Štúdium protinádorového účinku tomatidínu na modelu mamárneho karcinómu
Study of the anticancer effect of tomatidine on model of mammary carcinoma
Abstract:
Táto práca je zameraná na tomatidin, aglykonové jadro - tomatinu a jeho potenciálne účinky ako MDR modulátor. V teoretickej časti som sa zamerala hlavne na zhrnutie základných informácií o tomatidín a mnohopočetnej liekovej rezistencie, fenomén spôsobujúci rezistenciu na široké spektrum chemoterapeutík, a ABC transportéroch, ktoré sa priamo podieľajú na vzniku MDR. V experimentálnej časti sme sa zamerali …moreAbstract:
This study is focused on the tomatidine, the aglycone of - tomatine and its potential effect as MDR modulator. In the theoretical part are subscribed main information about tomatidine and multidrug resistance, a phenomenon of resistance to a wide spectrum of chemotherapeutics agents, and ABC transporters, which are directly involved in the genesis of MDR origin. The research part is focused on in vivo …more
Language used: Czech
Date on which the thesis was submitted / produced: 9. 5. 2014
Thesis defence
- Date of defence: 3. 6. 2014
- Supervisor: MUDr. Pavel Tomšík, Ph.D.
Citation record
ISO 690-compliant citation record:
LIEROVÁ, Anna. \textit{Štúdium protinádorového účinku tomatidínu na modelu mamárneho karcinómu}. Online. Master's thesis. Pardubice: University of Pardubice, Faculty of Chemical Technology. 2014. Available from: https://theses.cz/id/20mh00/.
The right form of listing the thesis as a source quoted
Lierová, Anna. Štúdium protinádorového účinku tomatidínu na modelu mamárneho karcinómu. Pardubice, 2014. diplomová práce (Mgr.). Univerzita Pardubice. Fakulta chemicko-technologická
Full text of thesis
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Institution archiving the thesis and making it accessible: Univerzita Pardubice, Fakulta chemicko-technologickáUniversity of Pardubice
Faculty of Chemical TechnologyMaster programme / field:
Special Chemical and Biological Programmes / Analysis of Biological Materials