Mgr. Karel Kubíček, PhD.

Doctoral thesis

NMR Charakterization of Protein - Protein and Protein - Cofactor Interactions

NMR Charakterization of Protein - Protein and Protein - Cofactor Interactions
Abstract:
Předkládaná práce popisuje nejdříve interakci mezi cytochromem c a cytochromem b5, které utváří modelový komplex pro přenos elektronu. Přestože tento komplex byl již v minulosti podroben zevrubnému zkoumání, nebylo dosud možné jej studovat pozorováním cytochromu c. Dále je v této práci popsána interakce mezi měděným iontem a proteinem DR1885 z Deinococcus radiodurans, který se pravděpodobně podílí …more
Abstract:
The here presented work provides first further information on the interaction between cytochrome c and cytochrome b5 that are forming a model electron transfer complex which has never before been studied from the side of cytochrome c. Secondly, interaction of a copper with protein DR1885 from Deinococcus radiodurans, that is probably involved in the assembly of CuA center of bacterial cytochrome c …more
 
 
Language used: English
Date on which the thesis was submitted / produced: 20. 11. 2007

Thesis defence

  • Date of defence: 23. 11. 2007
  • Supervisor: prof. RNDr. Vladimír Sklenář, DrSc.
  • Reader: Ing. Marek Kuzma, Ing. Richard Hrabal, CSc., prof. Ing. Antonín Lyčka, DrSc.

Citation record

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta

Masaryk University

Faculty of Science

Doctoral programme / field:
Biochemistry (4-years) / Biomolecular Chemistry