Bc. Miriam Štolcová

Bachelor's thesis

Stabilita antipsychotik v suché krevní skrvně

Stability of antipsychotics in a dried blood spot
Abstract:
Dried blood spot (DBS) is a form of taking a very small sample of capillary blood from patient. Before implementing the use of a new method of sampling for an analyte, it is always necessary to assess it‘s stability during the process. This bachelor‘s thesis is concerned with stability of clozapine in DBS. We were working with hypothesis, that clozapine will show good stability in DBS even after two …more
Abstract:
Suchá krvná škvrna (DBS) je forma odoberania veľmi malej vzorky kapilárnej krvi od pacienta. Pred zavedením využívania novej metódy vzorkovania pre analyt je vždy nutné pri nej posúdiť stabilitu daného analytu. Táto bakalárska práca sa zameriava na stabilitu klozapínu v DBS. Bolo pracované s hypotézou, že klozapín bude v DBS vykazovať dobrú stabilitu aj po dvoch týždňoch skladovania za predpokladu …more
 

Keywords

suchá krvná škvrna antipsychotiká klozapín HPLC stabilita dried blood spot antipsychotics clozapine stability
 
Language used: Slovak
Date on which the thesis was submitted / produced: 1. 6. 2021
Identifier: https://is.muni.cz/th/bjhj1/

Thesis defence

  • Date of defence: 8. 7. 2021
  • Supervisor: Mgr. Marta Pelcová, Ph.D.
  • Reader: Mgr. et Mgr. Lenka Michalcová, Ph.D.

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta
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