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Mgr. David Střelák

Advanced ('rigorózní') thesis

Acceleration of image processing algorithms for single particle analysis by electron microscopy

Acceleration of image processing algorithms for single particle analysis by electron microscopy
Abstract:
Kryogenní Elektronová Mikroskopie (Cryo-EM) je důležitá oblast současné strukturální biologie. Moderní elektronové mikroskopy produkují během relace terabajty dat, která se následně zpracovávají několik dní. K tomu, abychom získali rekonstruovanou částici v téměř atomárním rozlišení, potřebujeme zpracovat stovky tisíc projekcí. Cílem těchto tezí je vylepšit algoritmy používané v Cryo-EM, především …more
Abstract:
Cryogenic Electron Microscopy (Cryo-EM) is a very important field in the current structural biology. Modern electron microscopes can produce terabytes of data per single session, which takes days to process. Typically, hundreds of thousands of particles need to be used during the 3D refinement to obtain a near-atomic resolution. The goal of this thesis proposal is to improve the algorithms used in …more
 

Keywords

Cryo-EM SPA HPC Autotuning GPU Optimization Performance
 
Language used: English
Date on which the thesis was submitted / produced: 20. 2. 2020
Identifier: https://is.muni.cz/th/tt7i8/

Thesis defence

  • Date of defence: 27. 5. 2020
  • Reader: doc. Ing. Jiří Jaroš, Ph.D., Jose-Jesus Fernandez, PhD

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Fakulta informatiky
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Masaryk University

Faculty of Informatics

Advanced ('rigorózní řízení') programme / field:
Computer systems, communication and security / Computer systems, communication and security

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