Post-transcriptional regulation of TbIF1 in life cycle of Trypanosoma brucei – Sascha GRATZL
Sascha GRATZL
Bachelor's thesis
Post-transcriptional regulation of TbIF1 in life cycle of Trypanosoma brucei
Post-transcriptional regulation of TbIF1 expression in life cycle of \kur{Trypanosoma brucei}
Abstract:
TbIF1, a protein Inhibitor of F1-ATPase in Trypanosoma brucei, is expressed exclusively in the insect stage of the parasite. In the bloodstream form, TbIF1 is switched off, because its activity interferes with the essential role of the ATP synthase in the maintenance of the mitochondrial membrane potential. Here, we employ a series of reporter genes to study the impact of 3'UTR of TbIF1 on mRNA stability …moreAbstract:
TbIF1, a protein Inhibitor of F1-ATPase in Trypanosoma brucei, is expressed exclusively in the insect stage of the parasite. In the bloodstream form, TbIF1 is switched off, because its activity interferes with the essential role of the ATP synthase in the maintenance of the mitochondrial membrane potential. Here, we employ a series of reporter genes to study the impact of 3'UTR of TbIF1 on mRNA stability …more
Language used: English
Date on which the thesis was submitted / produced: 21. 5. 2020
Thesis defence
- Supervisor: Mgr. Ondřej Gahura, Ph.D.
Citation record
ISO 690-compliant citation record:
GRATZL, Sascha. \textit{Post-transcriptional regulation of TbIF1 in life cycle of Trypanosoma brucei}. Online. Bachelor's thesis. České Budějovice: University of South Bohemia in České Budějovice, Faculty of Science. 2020. Available from: https://theses.cz/id/bpcjwy/.
The right form of listing the thesis as a source quoted
GRATZL, Sascha. Post-transcriptional regulation of TbIF1 in life cycle of Trypanosoma brucei. Č. Budějovice, 2020. bakalářská práce (Bc.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
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Institution archiving the thesis and making it accessible: JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH, Přírodovědecká fakultaUNIVERSITY OF SOUTH BOHEMIA IN ČESKÉ BUDĚJOVICE
Faculty of ScienceBachelor programme / field:
Biochemistry / Biological Chemistry
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