Bc. Jana Jančovičová

Bachelor's thesis

Význam mikroRNA v molekulární patologii renálního karcinomu

Significance of microRNAs in molecular pathology of renal cell carcinoma
Abstract:
In our study, we collected group of 38 patients with localized or locally advanced clear-cell renal cell carcinoma (included 38 malignant tissue samples and 10 kidney tissue samples). We isolated miRNA in required quantity and quality. Using RT-PCR method we received expression levels of selected miRNA (miRNA-155, miRNA-141, miRNA-210, miRNA-200b, miRNA-200c, miRNA-106a, miRNA-106b, miRNA-182) in all …more
Abstract:
Vytvorili sme súbor 38 pacientov s lokalizovaným alebo lokálne pokročilým svetlobunečným karcinómom (z nich 38 vzoriek tumoru, 10 vzoriek obličkového parenchýmu). Vyizolovali sme miRNA v potrebnom množstve a kvalite. Pomocou metódy Real-Time PCR sme získali hladiny expresie vybraných miRNA (miRNA-155, miRNA-141, miRNA-210, miRNA-200b, miRNA-200c, miRNA-106a, miRNA-106b, miRNA-182) u všetkých 48 študovaných …more
 
 
Language used: Slovak
Date on which the thesis was submitted / produced: 13. 5. 2010

Thesis defence

  • Date of defence: 14. 6. 2010
  • Supervisor: doc. RNDr. Ondřej Slabý, Ph.D.

Citation record

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta