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Eva Vepřková

Bachelor's thesis

Syntéza monokvarterních reaktivátorů acetylcholinesterasy nesoucích (alkoxymethylen)bis-benzenový periferní ligand

Synthesis of monoquaternary acetylcholinesterase reactivators bearing (alcoxymethylene)bis-benzene peripheral ligand
Abstract:
The main aim of this Bachelor Thesis was synthesis of monoquaternary acetylcholinesterase reactivators bearing lipophilic peripheral site ligand. The Bachelor Thesis is divided into two parts, theoretical and experimental. The theoretical part deals with the issue of nerve agent intoxication and their current antidotal therapy. The antidotal therapy of nerve agent poisoning consists in administration …more
 

Keywords

Acetylcholinesterase Nerve agents Antidotal therapy Oxime reactivators
 
Language used: English
Date on which the thesis was submitted / produced: 10. 5. 2021
Identifier: http://evskp.uhk.cz/eB12856

Thesis defence

  • Date of defence: 8. 6. 2021
  • Supervisor: Mgr. Eugenie Nepovimová, Ph.D.
  • Reader: RNDr. Patrik Olekšák, PhD.

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Full text of thesis

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  • Soubory jsou od 30. 6. 2024 dostupné: světu
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Institution archiving the thesis and making it accessible: Univerzita Hradec Králové