Computational Study on Lectin-Carbohydrate Complexes – Navnit Kumar Mishra, M.Sc.
Navnit Kumar Mishra, M.Sc.
Doctoral thesis
Computational Study on Lectin-Carbohydrate Complexes
Computational Study on Lectin-Carbohydrate Complexes
Abstract:
Dizertační práce je zaměřena na studium interakcí mezi lektiny a cukry. Práce se detailněji zaměřila na lektin II (PAII-L) z bakterie Pseudomonas aeruginosa. Tato baktérie je vysoce toxická a je o ní známo, že se kolonizuje v biofilmech, na jejichž tvorbě se lektin podílí. Pro pochopení vazebné afinity fukosy, mannosy, galaktosy, glukosy, arabinosy a jejich methylovaných derivátů k PAII-L bylo provedeno …moreAbstract:
The dissertation thesis presented here is focused on study of lectin-carbohydrate interactions. The study has been carried out on Pseudomonas aeruginosa lectin-II (PA-IIL). This bacterium is highly toxic and it is know that the lectin participates in the toxicity by formation of biofilms. Molecular simulations have been performed to observe the consequences of PA-IIL lectin affinity towards fucose …more
Language used: English
Date on which the thesis was submitted / produced: 2. 9. 2009
Identifier:
https://is.muni.cz/th/rc4xj/
Thesis defence
- Date of defence: 24. 9. 2009
- Supervisor: prof. RNDr. Jaroslav Koča, DrSc.
- Reader: Mgr. Michal Kutý, Ph.D., Mgr. Kamila Réblová, Ph.D.
Citation record
Full text of thesis
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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakultaMasaryk University
Faculty of ScienceDoctoral programme / field:
Biochemistry (4-years) / Biomolecular Chemistry
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