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Bc. Zuzana Žufanová

Master's thesis

Bioinformatická analýza potenciálních glykosyltransferas z Mycobacterium tuberculosis

Bioinformatical analysis of putative glycosyltransferases from Mycobacterium tuberculosis
Abstract:
Mycobacterium tuberculosis je patogenní bakterie, která svoji obranu proti imunitnímu systému hostitele zakládá mimo jiné na buněčné stěně. Tato práce se zabývá vybranými hypotetickými proteiny z M. tuberculosis CDC1551 s cílem nalézt glykosyltransferasy, které se podílí na stavbě buněčné stěny, díky čemuž jsou zajímavými terapeutickými cíli v boji proti této bakterii. Hypotetické proteiny byly srovnávány …more
Abstract:
Mycobacterium tuberculosis is a pathogenic bacterium. Its cell wall protects it against the immune system of the host. This thesis deals with selected hypothetical proteins from M. tuberculosis CDC1551 to find glycosyltransferases that are involved in cell wall synthesis. That makes them an interesting therapeutic target for fighting this bacterium. Hypothetical proteins were compared with described …more
 

Keywords

glykosyltransferasy Mycobacterium tuberculosis hypotetický protein I-TASSER RaptorX Phyre BLAST HCA glycosyltransferases hypothetical protein
 
Language used: Czech
Date on which the thesis was submitted / produced: 16. 5. 2016
Identifier: https://is.muni.cz/th/esvws/

Thesis defence

  • Date of defence: 21. 6. 2016
  • Supervisor: prof. RNDr. Michaela Wimmerová, Ph.D.
  • Reader: Mgr. Josef Houser, Ph.D.

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta
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Masaryk University

Faculty of Science

Master programme / field:
Biochemistry / Chemoinformatics and Bioinformatics

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