Identification and Characterisation of Tau Minimal Regions as Potential Pharmacological Targets Against Tau Spreading in Tauopathies – Narendran ANNADURAI
Narendran ANNADURAI
Doctoral thesis
Identification and Characterisation of Tau Minimal Regions as Potential Pharmacological Targets Against Tau Spreading in Tauopathies
Identification and Characterisation of Tau Minimal Regions as Potential Pharmacological Targets Against Tau Spreading in Tauopathies
Abstract:
Tau, a microtubule-associated protein present abundantly in neurons of the central nervous system, stabilises axonal microtubules, providing structural architecture to axons. Tau aggregation occurs in many neurodegenerative diseases collectively termed 'tauopathies', characterised by the intracellular deposits of fibrillar tau tangles. Tau seeding, the ability of prion-like tau to recruit and misfold …more
Language used: English
Date on which the thesis was submitted / produced: 7. 2. 2023
Thesis defence
- Supervisor: Mgr. Viswanath Das, PhD.
Citation record
ISO 690-compliant citation record:
ANNADURAI, Narendran. \textit{Identification and Characterisation of Tau Minimal Regions as Potential Pharmacological Targets Against Tau Spreading in Tauopathies}. Online. Doctoral theses, Dissertations. Olomouc: Palacký University Olomouc, Faculty of Medicine and Dentistry. 2023. Available from: https://theses.cz/id/wefszj/.
The right form of listing the thesis as a source quoted
ANNADURAI, Narendran. Identification and Characterisation of Tau Minimal Regions as Potential Pharmacological Targets Against Tau Spreading in Tauopathies. Olomouc, 2023. disertační práce (Ph.D.). UNIVERZITA PALACKÉHO V OLOMOUCI. Lékařská fakulta
Full text of thesis
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Institution archiving the thesis and making it accessible: UNIVERZITA PALACKÉHO V OLOMOUCI, Lékařská fakultaPalacký University Olomouc
Faculty of Medicine and DentistryDoctoral programme / field:
Pediatrics / Pediatrics
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MARKLOVÁ, E.
11/2/2023