The effect of praziquantel exposure on red blood cells in grass carp (Ctenopharyngodon idella)

Noe HORIUCHI

Bakalářská práce

Abstract:

The aim of this study was to evaluate the effects of a short-term (96-hour) bath treatment with the addition of 2 mg/L and 4 mg/L of praziquantel (PZQ), on the red blood cell profile in grass carp (Ctenopharyngodon idella). The statistical analysis showed that the used concentrations of PZQ caused no significant differences (p > 0.05) between the values of the red blood cell profile and the calculated Wintrobe's parameters. This is indicative of a potential therapeutic dosage against selected endoparasites. Further studies would help provide the basis for the registration of Praziquantel drug in aquacultural industries within the European Union.

Abstract:

The aim of this study was to evaluate the effects of a short-term (96-hour) bath treatment with the addition of 2 mg/L and 4 mg/L of praziquantel (PZQ), on the red blood cell profile in grass carp (Ctenopharyngodon idella). The statistical analysis showed that the used concentrations of PZQ caused no significant differences (p > 0.05) between the values of the red blood cell profile and the calculated Wintrobe's parameters. This is indicative of a potential therapeutic dosage against selected endoparasites. Further studies would help provide the basis for the registration of Praziquantel drug in aquacultural industries within the European Union.

Keywords

antiparasitic, erythrocyte, haematocrit, haemoglobin, Wintrobe´s index, fish

Jazyk práce: angličtina

Datum vytvoření / odevzdání či podání práce: 14. 4. 2025

Zveřejnit od: 31. 12. 2999

Obhajoba závěrečné práce

• Vedoucí: doc. MVDr. Radka Dobšíková, Ph.D.

Veterinární univerzita Brno

Fakulta veterinární hygieny a ekologie

Bakalářský studijní program / obor:
Animal Protection and Welfare / Animal Protection and Welfare