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Mgr. Kateřina Sejpková

Bachelor's thesis

Vliv hyaluronanu na nádorové buňky

Influence of hylauronan on tumour cells
Abstract:
V následující práci jsem shrnula současné poznatky o vlastnostech hyaluronanu a jeho působení v nádorovém bujení. Zjištěné poznatky dokazují, že jeho role v průběhu onkogeneze je naprosto klíčová. Jeho interakce stimulují buněčnou proliferaci a migraci, angiogenezi, maligní transformaci i chemorezistenci. Naopak inhibuje buněčnou apoptózu a imunitní protirakovinné působení. Zkoumaná problematika nabízí …more
Abstract:
In this bachelor thesis I summarized current information about hyaluronan properties and his influence in tumours. Discovered knowledge proved, that his role during oncogenesis is absolutely crucial. His interaction stimulates cell proliferation and migration, angiogenesis, malignant transformation and chemoresistence. In spite of inhibits apoptosis and immunology anti-oncogene influence.Studied problems …more
 

Keywords

kyselina hyaluronová hyaluronan CD44 RHAMM rakovina hyaluronic acid cancer
 
Language used: Czech
Date on which the thesis was submitted / produced: 14. 5. 2013
Identifier: https://is.muni.cz/th/c0szf/

Thesis defence

  • Date of defence: 4. 6. 2013
  • Supervisor: RNDr. Lenka Švihálková Šindlerová, Ph.D.

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta
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Masaryk University

Faculty of Science

Bachelor programme / field:
Experimental Biology / Special Biology

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