Genome instability: A pitfall in hESC s use in regenerative medicine – Mgr. Miriama Krutá, Ph.D.
Mgr. Miriama Krutá, Ph.D.
Doctoral thesis
Genome instability: A pitfall in hESC s use in regenerative medicine
Genome instability: A pitfall in hESC s use in regenerative medicine
Abstract:
Lidské kmenové embryonální buňky (hESC) představují důležitý potenciální nástroj buněčné terapie, významé v oblastech regenerativní medicíny, onkologie, gerontologie a ve zlepšování prognózy a kvality života pacientů. Bohužel nás etické a technické problémy omezují v izolaci nových linijí hESC dle individuálních požadavků paciencta a nutí nás využít dlouhodobé kultivace hESC in vitro. Dlouhodobá kultivace …moreAbstract:
Human embryonic stem cells (hESC) present a potential instrument of a cell therapy and might be useful in future regenerative medicine, oncology, gerontology and for improving patients` life quality. However, ethical and technical problems accompanying isolation of new hESC line for every individual patient force us to opt for long-term cultured lines of hESC instead. Long-term cultivation of hESC …more
Language used: English
Date on which the thesis was submitted / produced: 28. 5. 2014
Identifier:
https://is.muni.cz/th/tvz40/
Thesis defence
- Date of defence: 25. 6. 2014
- Supervisor: Mgr. Vladimír Rotrekl, Ph.D.
Citation record
ISO 690-compliant citation record:
KRUTÁ, Miriama. \textit{Genome instability: A pitfall in hESC s use in regenerative medicine}. Online. Doctoral theses, Dissertations. Brno: Masaryk University, Faculty of Medicine. 2014. Available from: https://theses.cz/id/96tih5/.
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Institution archiving the thesis and making it accessible: Masarykova univerzita, Lékařská fakultaMasaryk University
Faculty of MedicineDoctoral programme / field:
Medical Biology (4-years) / Medical Biology
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