Bc. Hana Skoupilová

Master's thesis

Genetická analýza smc5-6 mutant

Genetic analysis of smc5-6 mutants
Abstract:
V současné době jsou známy tři SMC (Structural Maintenance of Chromosomes) komplexy, které se podílejí na organizaci chromatinu a na procesech spojených s jeho dynamikou. Jsou to kohesin, kondensin a SMC5-6 komplex, jehož hlavní funkce nebyla doposud uspokojivě objasněna. Tato práce si klade za cíl nalézt funkční vztahy s interakčními partnery komplexu SMC5-6 a pomocí genetických metod poodhalit způsoby …more
Abstract:
There are three SMC (Structural Maintenance of Chromosomes) complexes known yet which are involved in the organization of chromatin and processes associated with its dynamics. They are the following: cohesin, condensin and SMC5-6 complex. The major function of the last named SMC5-6 complex has not been revealed yet. The main objective of this thesis was to study functional relationships between the …more
 
 
Language used: Czech
Date on which the thesis was submitted / produced: 18. 5. 2015

Thesis defence

  • Date of defence: 4. 6. 2015
  • Supervisor: doc. Mgr. Jan Paleček, Dr. rer. nat.

Citation record

Full text of thesis

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta