Mgr. Lucia Sommerová

Bachelor's thesis

Úloha proteinu AGR2 v procesu maligní přeměny buňky

The role of AGR2 protein in the process of malignant cell transformation
Abstract:
The anterior gradient protein family includes protein AGR2, whose overexpression is associated with cancer. The mechanism of its regulation is not fully understood, but due to its expression in different type of tumour, two ways were described: hormone-dependent regulation and hormone independent regulation, which is triggered by physiological stress. During the malignant transformation somatic cell …more
Abstract:
Medzi rodinu proteínov anterior gradient patrí i proteín AGR2, ktorého zvýšená expresia je spojená s nádorovým ochorením. Mechanizmus jeho regulácie nie je úplne objasnený, avšak na základe jeho expresie v odlišných typoch nádorov bola zistená hormonálne závislá regulácia rovnako ako cesta hormonálne nezávislá, ktorá je spúšťaná ako odpoveď na fyziologický stres bunky. Pri malígnej transformácii podlieha …more
 
 
Language used: Slovak
Date on which the thesis was submitted / produced: 14. 5. 2012

Thesis defence

  • Date of defence: 18. 6. 2012
  • Supervisor: doc. Mgr. Roman Hrstka, Ph.D.
  • Reader: Mgr. Eva Ondroušková, Ph.D.

Citation record

Full text of thesis

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Institution archiving the thesis and making it accessible: Masarykova univerzita, Přírodovědecká fakulta